Solid Dosage Form

Development Platform

Topical Formulation Development Platform

Oral Film Formulation Development Platform

Commercial Manufacturing

Innovative Product Development and Commercialization

Advantages of Oral Films

Improving Patient Adherence and Safety

Oral films offer several advantages, especially suitable for children, elderly, psychiatric patients, and those with swallowing difficulties. They dissolve rapidly upon contact with saliva on the tongue, eliminating the need for water, additional containers, or swallowing. This makes them convenient for on-the-go medication administration and suitable for conditions like motion sickness, allergies, coughs, or asthma attacks. Oral films also reduce the risk of choking or oral obstruction associated with conventional oral dosage forms, thereby enhancing medication safety and compliance for special patient groups such as children, elderly, psychiatric patients, those with memory or behavioral disorders, and bedridden patients.

Avoiding first-pass metabolism, reducing liver and kidney burden, and enhancing safety

By rapidly absorbing through the oral mucosa into the bloodstream, oral films avoid the hepatic first-pass effect and enzymatic metabolism in the gastrointestinal tract associated with conventional oral formulations. This enhances bioavailability, reduces dosage requirements, and lowers adverse effects. Additionally, direct entry into the systemic circulation allows for rapid onset of action, meeting clinical treatment needs for emergencies. Some drugs absorbed through the oral mucosa can also overcome food interactions.

Rapid drug release, quick onset of action, and enhanced bioavailability

Rapid drug release enables efficient and fast-acting effects.

Our Technological Advantages

1. Possesses a strong understanding of dosage forms and extensive experience in project development

3. A completely new masking system

5. Industrial-scale production

2. Precise Quality Control

4. Combining self-emulsification with transdermal permeation research techniques

Equipments for oral film formulations based on crystallization technology

Based on clinical applications of medications, we meticulously analyze the physicochemical properties of active ingredients, precisely targeting indications and optimal oral film dosage forms. Innovating patient medication habits, we enhance medication effectiveness, safety, and adherence to varying degrees.

Natural flavor masking agents have low sweetness and require larger amounts, which may not be suitable for diabetic patients. Many artificial sweeteners are limited in use due to concerns about their impact on the central nervous system development in children. Our unique flavor masking technology addresses these issues by modifying various properties of the drug, thereby significantly enhancing patient compliance, especially in children, while avoiding the mentioned concerns.

Seamless integration of pilot and small-scale trials during oral film formulation development reduces the risks associated between formulation development and production.

The oral film process is prone to inducing crystalline instability. Our company's precise quantification of crystalline forms and mature experience in targeted crystallization preparation can address oral film inherent polymorphism issues from the source. This approach minimizes clinical risks, resolves oral film stability, and enhances in vivo release consistency.

Developing multiple oral film formulations, integrating self-emulsification/transdermal permeation technologies to enhance bioavailability and address low drug loading issues.
Our company has prioritized the development of high-end formulations, successfully completing several advanced oral film formulations. We have implemented a systematic approach to the development of oral film formulations, bolstered by a standardized GMP facility that integrates both research and production capabilities.
Current projects and technological achievements in oral film formulations

We have independently developed a total of 12 varieties of oral film formulations.

We have developed 4 types of buccal films and 8 types of oral dissolving films.

We have independently developed 1 advanced oral film formulation.

We have obtained 3 granted invention patents for oral film products.

Solid State Research

Improving drug absorption through solid-state technology is the foundation of all innovative technologies at Xinyang Weikang.

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Innovative Improved Drugs
Our company strategically focuses on developing high-end formulations, successfully completing numerous advanced oral film formulations, and establishing a systematic approach to formulation development.
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CDMO
We are the only integrated domestic platform specializing in crystalline formulation production, strictly adhering to GMP standards. We specialize in scaling up research and commercial production of various dosage forms including oral films, topical formulations, and solid formulations.
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Nycrist Phamatech Co.,Ltd
Tel:19129598229  
       19129598368(Mr.Lee)
       19926561149(Mrs.Chen)
       19926414326(Mr.Liu)


Headquarters Address: Building A3, Guanming Technology Park, No. 3009 Guangming Avenue, Fenghuang Community, Fenghuang Street, Guangming District, Shenzhen


Production Base Address: Weiguang Life Science Park, Guangming District, Shenzhen


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HR:0755-23411222
      19145082504(Mr.lee)

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TEL:19129598229